Adam Meyer

Author: Expert reviewer:

January 4, 2023

Adam Meyer

By Adam Meyer

mbg Contributor

Adam Meyer is a health writer, certified holistic nutritionist, and 100 percent plant-based athlete. He graduated from the NutraPhoria School of Holistic Nutrition in 2019 and has since founded Pillars Nutrition. His work has been featured on EatingWell, Eat This Not That!, The Beet, Verywell Fit, The Healthy, Livestrong, Alive, Best Life and others.

Lauren Torrisi-Gorra, M.S., RD

Expert review by

Lauren Torrisi-Gorra, M.S., RD

Registered Dietitian

Lauren Torrisi-Gorra is a Registered Dietitian with a Grand Diplôme in Culinary Arts from the French Culinary Institute and a bachelor’s in Communication and Media Studies from Fordham University. After a decade working in the culinary and media worlds, Lauren pursued her ultimate passion and received her master’s degree in Clinical Nutrition and Dietetics at New York University.

woman drinking protein shake

Image by istock // VioletaStoimenova

January 4, 2023

Protein is the nutrient of choice when it comes to both muscle growth and fat loss. However, you may wonder, “Does protein make you gain or lose weight?” While protein is often touted for its weight loss benefits, it can also contribute to weight gain by helping your body build and maintain muscle mass.

We spoke with nutrition experts to help answer all your protein and weight gain questions.


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How protein can help you lose fat.

Protein is an essential macronutrient that plays a critical role in metabolic health—the ideal levels of blood sugar, triglycerides, cholesterol, blood pressure, and waist circumference—and several other bodily functions1 related to metabolism. Here are a few ways this important nutrient can help you lose fat if that’s a goal of yours:


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Improves insulin resistance.

Protein has an “insulinotropic effect3,” which encourages insulin secretion from your pancreas to help clear glucose (sugar) out of your blood.

Gabrielle Lyon, D.O., a functional medicine physician and the founder of the Institute for Muscle-Centric Medicine, tells mindbodygreen, “Protein can stabilize your blood sugar by preventing insulin spikes. Less insulin spiking means more sustained energy levels and fewer hunger pangs throughout the day.”


Enhances thermic effect of food (TEF).

TEF is the amount of energy4 required for your body to digest, absorb, metabolize, and store the food you eat. Protein has a higher thermic effect than carbs and fats since your body has to work harder to break it down and digest it, thus using more energy and burning more calories when consumed.

“Protein is a macronutrient that provides 4 calories per gram. Approximately 20% of calories consumed from protein are lost as heat compared to 5% with carbs,” says Layman, so eating more protein while reducing your carb intake is a surefire way to burn more fat.

“When comparing a high-carb, low-protein diet with a high-protein, reduced-carb diet (with subjects eating the same amount of calories), the protein group burned about 300 more calories each day,” Layman adds.


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Stimulates muscle protein synthesis (MPS).

Don’t forget the exercise.

If fat loss is your goal, an effective strategy is to combine a nutritious high-protein diet with regular cardio and strength training exercises.


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How protein can help you gain muscle:


Helps repair, build, and maintain muscle tissue.

High-protein diets have been found to promote gains in muscle mass11 when combined with resistance training, prevent loss of muscle mass12 during calorie restriction, and reduce the natural loss of muscle mass13 that occurs with aging.

If your goal is to gain lean muscle, pair your protein with healthy carbohydrates. Complex carbs in fruits, vegetables, whole grains, and legumes give you the energy required for strenuous exercise, while protein helps repair and build muscle. Essentially, your body won’t have the energy to allow protein to do its job without sufficient carb intake. Also, combining these two macronutrients helps stabilize blood sugar14 when consumed simultaneously. 

However, if you’re trying to lose weight and burn fat, you’ll want to increase your protein intake15 while reducing carbs. Conventional diets are generally low in fat and have a macronutrient breakdown16 of roughly 50% carbs, 20% protein, and 30% fats. For weight loss, these ranges should be adjusted to 10 to 30% carbs, 40 to 50% protein, and 30 to 40% fats.


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Helps increase strength.

If you regularly engage in resistance training, increasing your daily protein intake17 can boost overall lean body mass and lower-body muscle strength.

Protein is comprised of 20 amino acids18 (the building blocks of protein). Nine are essential, meaning your body doesn’t produce them and needs to acquire them through diet. The amino acid leucine plays a significant role in muscle development19. Leucine is one of three branched-chain amino acids (BCAAs)—the other two being valine and isoleucine—which are broken down in muscle tissue20 instead of the liver like other essential amino acids.

“When you eat high-quality protein that contains adequate amounts of leucine (around 2.5 grams), you turn on your body’s calorie-burning, muscle-building process for five to six hours,” says Lyon.

How much protein to eat a day.

Currently, the recommended dietary allowance (RDA) for protein is 0.8 gram per kilogram of body weight21 (g/kg/bw), regardless of your age, gender, weight, and activity level. However, if you’re an active person looking to gain muscle or lose fat, you’ll need more protein than the conservative RDA to reach your fitness goals.

There’s no one-size-fits-all approach to protein intake. That’s because the amount you need depends on several factors, including age, weight, and activity level. However, the American College of Sports Medicine (ACSM) recommends that athletes and active individuals up their daily protein intake to between 1.2 and 2.0 g/kg/bw22. For many people, that’s more than 120 grams of protein per day.

“Low protein intake halts muscle gain, but high-protein intake doesn’t ’cause’ muscle gain,” adds Layman. “You can enhance muscle protein synthesis with protein intakes of 1.2 to 1.8 g/kg/bw. Many athletes will reach 2.2 g/kg/bw (1 gram per pound).”

Is it possible to eat too much protein?

Similar to your daily protein needs, the “safe” amount of protein you can consume depends on your individual needs. An average healthy adult can generally eat up to 2.0 g/kg/bw daily and not experience side effects. However, chronic protein consumption of over 2.0 g/kg of body weight daily23 could potentially cause health issues in some people, such as:

  • Abdominal discomfort (indigestion, gas, bloating)
  • Exhaustion
  • Dehydration
  • Nausea
  • Irritability
  • Headache
  • Diarrhea

If you have kidney health issues such as chronic kidney disease (CKD), you must be careful with your protein intake24 since excess protein can cause waste to build up in your blood and your kidneys may be unable to remove all the extra waste. “For chronic kidney disease patients unable to regulate protein metabolism and fluid balance in the body, too much protein can be harmful,” cautions Lyon.

Best types of protein to eat.

In no particular order, here’s a list of high-quality protein sources to include more of in your diet to gain muscle and lose fat: 

  • Eggs (6 g/serving): Eggs are an excellent complete protein source that’s nutrient-dense and easy to digest. They’re also a good source of selenium and vitamin D25, which are difficult to obtain through diet. Also, eggs are high in the amino acid leucine26 (with one egg providing roughly 500 milligrams), which is essential for muscle-building.
  • Protein powder (25-30 g/serving): Look for a high-quality protein powder that provides at least 25 to 30 grams of protein and 2 to 3 grams of leucine per serving, is third-party tested, has no artificial sweeteners or preservatives, and contains as few ingredients as possible. Whey is a good choice since it’s a complete protein (meaning it contains adequate amounts of all nine essential amino acids).
  • Legumes (~8 g/serving): Lentils, beans, and peas are nutritional powerhouses that are not only high-quality sources of plant protein but are also low in fat27, free of cholesterol, and rich in fiber, healthy carbs, B vitamins, and minerals.
  • Quinoa (8 g/serving): Another complete plant protein source28, quinoa is gluten-free and delivers an array of essential nutrients, such as minerals, vitamins, dietary fibers, and healthy carbs.
  • Chia seeds (5 g/serving): These tiny but mighty seeds provide a variety of amino acids29 in addition to vitamins, minerals, fiber, and healthy omega-3 fatty acids. 
  • Soy (~10 g/serving): Foods such as tofu, tempeh, and edamame are excellent sources of complete plant protein that can reduce chronic disease risk30, including heart disease and breast and prostate cancer.

Best time of day to eat protein.

Research suggests that consuming protein within your anabolic window31 (30 minutes to two hours after a workout) enhances muscle repair and growth.

However, several studies32 have found that consistent protein intake throughout the day is more important for gaining muscle, promoting recovery, maximizing performance, and losing weight.

To optimize MPS, aim to consume 25 to 30 grams of high-quality protein21 during two or three meals throughout the day. This amount has been found sufficient for both younger and healthy older adults.

“In general, the first meal of the day after a nighttime fasting period is the most important for MPS,” says Layman. “However, if you’re eating a low protein diet (only 50 to 60 grams per day), getting at least one meal up around 40 grams is critical. If you have a higher protein intake (around 100 grams per day), it’s best to distribute the protein. The first and last meals will greatly benefit muscle growth.”

“Eating a high-protein meal every four to six hours during feeding windows will maintain your body in an anabolic state with ongoing muscle protein synthesis,” Lyon explains. “The first and last meals of the day are most important because they’re when you break your overnight fasting period and prepare your body for sleep, where you do most of your repair and regenerate activities.”

Frequently Asked Questions

Does protein make you gain fat or muscle?

Protein itself doesn’t make you gain fat or muscle. While it promotes muscle growth and repair, eating anything in a calorie surplus causes weight gain. However, since protein has a higher thermic effect than carbs, a higher-protein, lower-carb diet will help reduce body fat during weight loss.

Does protein make you gain weight without working out?

The primary driver of weight gain is excess calorie consumption, not protein. “Weight gain from protein depends on how many calories you’re consuming and how much protein you’re getting with each meal,” says Lyon.

How can I use protein powders for weight gain?

To use protein powders for weight gain from muscle mass, Lyon advises, “Protein powders can be used at any meal for a quick and convenient way of getting the protein boost your body needs for muscle protein synthesis. Typically, people will do a post-workout protein shake or smoothie to jump-start their recovery. Protein powder can also be added to various recipes to increase the protein content of common foods.”

The takeaway.

Protein is a powerful macronutrient that plays a critical role in several metabolic functions, including muscle growth and healthy weight management. Eating a wide variety of high-quality protein sources (like those in some of these high-protein breakfast recipes) can help you reach your health and fitness goals. Talk to your doctor or a registered dietitian if you want to learn more or have further questions about your protein intake.